The European Commission published a draft regulation that lowers the specific migration limit (SML) for BPA from plastic food-contact materials in line with the EFSA opinion published in January 2015. Taking into account uncertainties surrounding potential health effects of BPA on the mammary gland, reproductive, metabolic, neurobehavioral and immune systems, the overall uncertainty factor was increased and applied to establish a new Tolerable Daily Intake (TDI). On the basis of a new “temporary” tolerable daily intake (t-TDI), the allocation factor, and the exposure assumption, the SML is limiting from 0.6mg to 0.05 mg of BPA per kg of food (mg/kg). The Authority designated the TDI as temporary pending the outcome of a long-term toxicity study on BPA in rodents, currently being undertaken by FDA and the National Toxicology Program. USP has also been focusing on its plastic packaging standards, indicating in a revision to its <661> that packaging materials for oral solids and topicals are considered safe if they are compliant with food regulations (IPQ August 26, In Brief).
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